3840 (tel. 220 443 840)
Education and Qualification.
1996- Research Assistant at the NMR laboratory, UCT Prague
1994 One year stay at the Organic Chemistry Department of the University of Leicester (Great Britain)
1991 Ph.D. in organic chemistry, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague. Thesis: Acyclic Analogues of Nucleosides and Nucleotides with Modified Purine Bases
1983-1995 Research Assistant at the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague
1978 MSc. in organic chemistry, UCT Prague (theme: Electrochemical oxidations of bezofuranes)
Research interests
Application of high resolution NMR spectroscopy in the field of calixarenes, resorcinarenes and natural compounds. Studies of conformational a dynamic properties of molecules; kinetics and thermodynamics of chemical reactions.
Selected publications
Krovacek M., Dvorakova H., Votruba I., Cisarova I., Dvorak D. (2012) 6-Alkynylpurines bearing electron acceptor substituents: preparation, reactivity in cycloaddition reactions and cytostatic activity. Collection of Czechoslovak Chemical Communications, 76(12), 1487-1507. doi:10.1135/cccc2011176
Kundrat O., Dvorakova H., Bohm S., Eigner V., Lhotak P. (2012) S-Alkylation of Thiacalixarenes: How the Regio- and Stereoselectivities Depend on the Starting Conformation. Journal of Organic Chemistry, 77(5), 2272-2278. doi:10.1021/jo202571h
Kaminsky J., Dvorakova H., Stursa J., Moravcova J. (2011) Collection of Czechoslovak Chemical Communications, 76(10), 1199-1222. doi:10.1135/cccc2010104
Menova P., Eigner V., Cejka J., Dvorakova H., Sanda M., Cibulka R. (2011) Synthesis and structural studies of flavin and alloxazine adducts with O-nucleophiles. Journal of Molecular Structure, 1004(1-3), 178-187. doi:10.1016/j.molstruc.2011.08.002
Kundrat O., Eigner V., Dvorakova H., Lhotak P. (2011) S-Alkylation of Thiacalixarenes: A Long-Neglected Possibility in the Calixarene Family. Organic Letters, 13(15), 4032-4035. doi:10.1021/ol201546y
Menova P., Kafka F., Dvorakova H., Gunnoo S., Sanda M., Cibulka R. (2011) Pyrazinium Salts as Efficient Organocatalysts of Mild Oxidations with Hydrogen Peroxide. Advanced Synthesis & Catalysis. 353(6), 865-870. doi:10.1002/adsc.201000906
Jurok R., Cibulka R., Dvorakova H., Hampl F., Hodacova J. (2010) Planar Chiral Flavinium Salts - Prospective Catalysts for Enantioselective Sulfoxidation Reactions. European Journal of Organic Chemistry. (27), 5217-5224 doi:10.1002/ejoc.201000592
Chlubnova I., Filipp D., Spiwok V., Dvorakova H., Daniellou R., Nugier-Chauvin Caroline,. Kralova B., Ferrieres V. (2010) Enzymatic synthesis of oligo-D-galactofuranosides and L-arabinofuranosides: from molecular dynamics to immunological assays. Organic & Biomolecular Chemistry. 8(9), 2092-2102. doi:10.1039/b926988f
Dolensky B., Kvicala J., Paleta O., Lang J., Dvorakova H., Cejka J. (2010) Trifluoromethylated (tetrahydropyrrolo) quinazolinones by a new three-component reaction and facile assignment of the regio- and stereoisomers formed by NMR spectroscopy. Magnetic Resonance in Chemistry, 48(5), 375-385. doi:10.1002/mrc.2580
Benesova E., Lipovova P., Dvorakova H., Kralova B. (2010) ß-d-Galactosidase from Paenibacillus thiaminolyticus catalyzing transfucosylation reactions. Glycobiology, 20(4), 442-451. doi:10.1093/glycob/cwp196
Hornicek J., Dvorakova H., Bour P. (2010) Intramolecular Proton Transfer in Calixphyrin Derivatives. Journal of Physical Chemistry A, 114(10), 3649-3654. doi:10.1021/jp911598w
Zurek J., Cibulka R., Dvorakova H., Svoboda J. (2010) N 1,N 10-Ethylene-bridged flavinium salts derived from -valinol: synthesis and catalytic activity in H2O2 oxidations. Tetrahedron Letters, 51(7), 1083-1086. doi:10.1016/j.tetlet.2009.12.096
Kundrat O., Dvorakova H., Eigner V., Lhotak P. (2010) Uncommon Regioselectivity in the Thiacalix[4]arene Series: Gross Formylation of the Cone Conformer. Journal of Organic Chemistry, 75(2), 407-411. doi:10.1021/jo902240h
Kundrat, O., Dvorakova, H., Cisarova, I., Pojarova, M., Lhotak, P. (2009) Org. Lett. 11, 4188-4191. doi:10.1021/ol901812m
Keder, R., Dvorakova, H., Dvorak, D. (2009) Eur. J. Org. Chem. 1522-1531. doi:10.1002/ejoc.200801002
Simanova, M., Dvorakova, H., Stibor, I., Pojarova, M., Lhotak, P. (2008) Tetrahedron Lett. 49, 1026-1029. doi:10.1016/j.tetlet.2007.12.004
Dvorakova, H., Lang, J., Vlach, J., Sykora, J., Cajan, M., Himl, M., Pojarova, M., Stibor, I., Lhotak, P. (2007) J. Org. Chem. 72, 7157-7166. doi:10.1021/jo070927i
Tobrman, T., Meca, L., Dvorakova, H., Cerny, J., Dvorak, D. (2006) Organometallics 25, 5540-5548. doi:10.1021/om0605837
Dvorakova, H., Stursa, J., Cajan, M., Moravcova, J. (2006) Eur. J. Org. Chem. 4519-4527. doi:10.1002/ejoc.200600386
Bernatkova, M., Dvorakova, H., Andrioletti, B., Kral, V., Bour, P. (2005) J. Phys. Chem. A 109, 5518-5526. doi:10.1021/jp050746p
Dolensky, B., Kroulik, J., Kral, V., Sessler, J. L., Dvorakova, H., Bour, P., Bernatkova, M., Bucher, C., Lynch, V. (2004) J. Am. Chem. Soc. 126, 13714-13722. doi:10.1021/ja048075g
Novak, J., Linhart, I., Dvorakova, H. (2004) Eur. J. Org. Chem. 2738-2746. doi:10.1002/ejoc.200300811
Stastny, V., Stibor, I., Dvorakova, H., Lhotak, P. (2004) Tetrahedron 60, 3383-3391. doi:10.1016/j.tet.2004.02.036
Stursa, J., Dvorakova, H., Smidrkal, J., Petrickova, H., Moravcova, J. (2004) Tetrahedron Lett. 45, 2043-2046. doi:10.1016/j.tetlet.2004.01.080
Lhotak, P., Himl, M., Stibor, I., Sykora, J., Dvorakova, H., Lang, J., Petrickova, H. (2003) Tetrahedron 59, 7581-7585. doi:10.1016/S0040-4020(03)01171-2
Hocek, M. Dvorakova, H. (2003) J. Org. Chem. 68, 5773-5776. doi:10.1021/jo034351i
Dvorakova, H., Masojidkova, M., Holy, A., Balzarini, J., Andrei, G., Snoeck, R., DeClercq, E. (1996) J. Med. Chem. 39, 3263-3268. doi:
Dvorakova, H., Dvorak, D., Holy, A. (1996) Tetrahedron Lett. 37, 1285-1288.